Genetic Variants of Mucins: Unexplored Conundrum

THE CONUNDRUM OF EUTHANASIA

The Conundrum of Genetic “Drivers” in Benign Conditions

Advances in deep genomic sequencing have identified a spectrum of cancer-specific passenger and driver aberrations. Clones with driver anomalies are believed to be positively selected during carcinogenesis. Accumulating evidence, however, shows that genomic alterations, such as those inBRAF,RAS,EGFR,HER2,FGFR3,PIK3CA,TP53,CDKN2A, andNF1/2, all of which are considered hallmark drivers of specifi...

automatic verification of authentication protocols using genetic programming

implicit and unobserved errors and vulnerabilities issues usually arise in cryptographic protocols and especially in authentication protocols. this may enable an attacker to make serious damages to the desired system, such as having the access to or changing secret documents, interfering in bank transactions, having access to users’ accounts, or may be having the control all over the syste...

functional genetic variants of foxp3 and risk of multiple sclerosis

background multiple sclerosis (ms) is an autoimmune disease that affects the central nervous system (cns). ms is one of the most common cause of neurological impairment at a young age with a complex etiology. the forkhead/winged helix (foxp3) gene encodes a transcription factor that plays an important role in the working and progress of regulatory t cells. loss of the foxp3 function impairs the...

Genetic Variants of Γg4 Globulin

Two types of gammaG4 proteins, termed 4a and 4b, were characterized through antigenic studies of myeloma proteins. Both were recognized by specific antigens on the Fc fragment which were shared with other gammaG classes. The distinctive antigen of the common 4a type was shared with all gammaG1 and gammaG3 proteins but missing in those of the gammaG2 class; that for the rarer 4b type was selecti...